KMID : 0607520210290020121
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Korean Journal of Psychosomatic Medicine 2021 Volume.29 No. 2 p.121 ~ p.127
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The Association Between Cancer and Network Structure of Depressive Symptoms
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Hwang Hwi-Jin
Lee Kyung-Kyu Lee Seok-Bum Lee Jung-Jae Kim Kyoung-Min Kim Do-Hyun
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Abstract
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Objectives£ºThe characteristics of depressive symptoms in patients with cancer is different from those in control group. However, few research has focused on the association between depressive symptoms in cancer patients. The aim of this study was to compare the network structure of depressive symptoms between patients with cancer and normal control.
Methods£ºThis study was based on cohort data from Korea National Health and Nutrition Examination Survey in 2016-2018. The Patient health Quetionnaire-9 (PHQ-9) was used to assess depressive symptoms in 599 patients with cancer and 599 age-sex matched controls. We estimated network structure of depressive symptom using Isingfit model.
Results£ºThere was no significant difference of each PHQ-9 item score. There were strong associations between symptoms were concentration problem-psychomotor activity, anhedonia-depressed mood, and depressed mood-suicidal ideation in both groups. Strength centrality of worthlessness was significantly higher in patients with cancer.
Conclusions£ºThese results suggest that worthless is associated with other depressive symptoms more tightly in patients with cancer. Worthless can serve as important treatment targets for intervention of depression in patients with cancer.
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KEYWORD
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Cancer, Depression, Network analysis, Centrality
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